Testosterone Replacement Therapy (TRT) comes into play when the body lacks or experiences a reduction in testosterone hormone levels. This condition, known as testosterone deficiency or hypogonadism, can arise due to various factors including aging, obesity, medications, and medical history, such as cancer. As men age, the concentration of testosterone in their body naturally declines.

Hypogonadism affects an estimated 4 to 5 million men in the United States alone. Research indicates that this condition is frequently underdiagnosed and undertreated in adult males. This oversight might occur because the symptoms are often attributed to the aging process or other medical issues, sometimes even disregarded by both patients and medical practitioners. Astonishingly, only about 5% of men with hypogonadism undergo testosterone replacement therapy. Consequently, there’s a need to redefine what’s considered a normal testosterone level and reconsider the threshold for treatment.

The evaluation of hypogonadism involves a series of blood tests prescribed by a healthcare professional.

Low testosterone levels can result in various unwanted effects, including:

• Sexual dysfunction, reduced libido, and loss of morning erections
• Decreased bone density and increased risk of fractures
• Diminished muscle mass and strength
• Accumulation of abdominal fat
• Anemia or low blood cell counts
• Increased fatigue
• Feelings of depression or irritability

When considering testosterone replacement therapy, patients must ensure that a knowledgeable and experienced physician, well-versed in the potential risks of overdoing treatment, oversees their care. The primary objective is to harmonize hormone levels with minimal side effects.